Deletion of the 500KB 16p11.2 region has been discovered as a major risk factor for autism spectrum disorder. Our laboratory […]
Rett Syndrome (RTT) is a devastating neurodevelopmental disorder and the leading known genetic cause of autism in girls. Mutations in […]
Our laboratory has revealed novel and critical roles for astrocytes in brain function. By two-photon imaging of neurons and astrocytes […]
Inhibitory interneurons of the visual cortex powerfully shape the responses of their target cells. As our knowledge of cortical inhibitory […]
We use several model systems to study developmental plasticity in the cortex and its mechanisms. The first, which we pioneered, […]
Understanding how the brain makes perceptual decisions and generates action signals is a fundamental goal of neuroscience. Anatomical studies demonstrate […]
[Source: MIT News, April 27, 2015] Researchers at MIT’s Picower Institute for Learning and Memory have shown for the first […]
The motley group included men and women, old and young, in sweatshirts and three-piece suits, shod in socks and sandals, […]
Inhibitory neuron functionality is not an immutable property of cortical cells, but a consequence of more complex network dynamics. The […]
Monocular deprivation (MD) experiments have proven invaluable for investigating the cellular and molecular underpinnings of experience-dependent plasticity. MD during the […]