Deletion of the 500KB 16p11.2 region has been discovered as a major risk factor for autism spectrum disorder. Our laboratory […]
Rett Syndrome (RTT) is a devastating neurodevelopmental disorder and the leading known genetic cause of autism in girls. Mutations in […]
Our laboratory has revealed novel and critical roles for astrocytes in brain function. By two-photon imaging of neurons and astrocytes […]
Inhibitory interneurons of the visual cortex powerfully shape the responses of their target cells. As our knowledge of cortical inhibitory […]
We use several model systems to study developmental plasticity in the cortex and its mechanisms. The first, which we pioneered, […]
Understanding how the brain makes perceptual decisions and generates action signals is a fundamental goal of neuroscience. Anatomical studies demonstrate […]